8GJP

A1 Int graft: Adenylation domain 1 core construct from teicoplanin biosynthesis, intermediate selection pocket graft

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Non-ribosomal peptide synthetase	polymer	399	42095.7	2	UniProt (Q70AZ9) Pfam (PF00501) UniProt (by SIFTS) (A0A561VI36) In PDB	Actinoplanes teichomyceticus
2	C, D	MbtH-like short polypeptide	polymer	69	7636.3	2	UniProt (Q70AZ5) Pfam (PF03621) UniProt (by SIFTS) (Q6ZZJ2) In PDB	Actinoplanes teichomyceticus

Sequence modifications

A, B: 9 - 398 (UniProt: Q70AZ9)

PDB	External Database	Details
Met 8	-	initiating methionine
Tyr 237	His 237	engineered mutation
Val 295	Leu 295	engineered mutation
Gly 399	-	expression tag
Ser 400	-	expression tag
His 401	-	expression tag
His 402	-	expression tag
His 403	-	expression tag
His 404	-	expression tag
His 405	-	expression tag
His 406	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	99464.0
All*	Total formula weight	99464.0

*Water molecules are not included.