8GJB

L-threonine 3-Dehydrogenase from Trypanosoma cruzi in complex with NAD and acetate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	L-threonine 3-dehydrogenase	polymer	366	40503.5	2	UniProt (Q4CU39) Pfam (PF01370) In PDB	Trypanosoma cruzi
2	A, B	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
3	A, B	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
4	A, B	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
5	A, B	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6	B	2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		209.2	1	Chemie (BTB)
7		water	water		18.0	285	Chemie (HOH)

Sequence modifications

A, B: 1 - 332 (UniProt: Q4CU39)

PDB	External Database	Details
Met -33	-	initiating methionine
Gly -32	-	expression tag
Ser -31	-	expression tag
Ser -30	-	expression tag
His -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
Ser -23	-	expression tag
Ser -22	-	expression tag
Gly -21	-	expression tag
Leu -20	-	expression tag
Val -19	-	expression tag
Pro -18	-	expression tag
Arg -17	-	expression tag
Gly -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
Met -13	-	expression tag
Ala -12	-	expression tag
Ser -11	-	expression tag
Met -10	-	expression tag
Thr -9	-	expression tag
Gly -8	-	expression tag
Gly -7	-	expression tag
Gln -6	-	expression tag
Gln -5	-	expression tag
Met -4	-	expression tag
Gly -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	81007.0
Non-Polymers*	Number of molecules	9
	Total formula weight	1916.6
All*	Total formula weight	82923.6

*Water molecules are not included.