8GIH
Structure of Hepatitis B Virus Capsid Y132A mutant in complex with Compound 24
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Capsid protein | polymer | 160 | 18004.6 | 6 | UniProt (L7R9I1) Pfam (PF00906) | Hepatitis B virus (HBV) | Core antigen,Core protein,HBcAg,p21.5 |
| 2 | G, H, J, L, M... (A, B, C, D, E...) | CHLORIDE ION | non-polymer | 35.5 | 12 | Chemie (CL) | |||
| 3 | I, K, O, R, U... (A, B, C, D, E...) | (6S,8R)-N-(3-bromo-4-fluorophenyl)-8-fluoro-10-methyl-11-oxo-1,3,4,7,8,9,10,11-octahydro-2H-pyrido[4',3':3,4]pyrazolo[1,5-a][1,4]diazepine-2-carboxamide | non-polymer | 454.3 | 6 | Chemie (ZMH) | |||
| 4 | AA, BA, CA, DA, Y... (C, D, E, F, A...) | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 149 (UniProt: L7R9I1)
| PDB | External Database | Details |
|---|---|---|
| Met -2 | - | initiating methionine |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ala 132 | Tyr 132 | engineered mutation |
| Lys 150 | - | expression tag |
| Leu 151 | - | expression tag |
| Glu 152 | - | expression tag |
| Asn 153 | - | expression tag |
| Leu 154 | - | expression tag |
| Tyr 155 | - | expression tag |
| Phe 156 | - | expression tag |
| Gln 157 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 108027.5 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 3151.1 | |
| All* | Total formula weight | 111178.5 |
