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8GHB

The structure of h12-LOX in monomeric form

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Polyunsaturated fatty acid lipoxygenase ALOX12polymer66876451.51UniProt (P18054)
Pfam (PF01477)
Pfam (PF00305)
Homo sapiens (human)Arachidonate (12S)-lipoxygenase,12S-LOX,12S-lipoxygenase,Arachidonate (15S)-lipoxygenase,Linoleate (13S)-lipoxygenase,Lipoxin synthase 12-LO,Platelet-type lipoxygenase 12
2B
(A)
FE (II) IONnon-polymer55.81Chemie (FE2)
Sequence modifications
A: 2 - 663 (UniProt: P18054)
PDBExternal DatabaseDetails
His -4-expression tag
His -3-expression tag
His -2-expression tag
His -1-expression tag
His 0-expression tag
His 1-expression tag
Ser 322Asn 322variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight76451.5
Non-Polymers*Number of molecules1
Total formula weight55.8
All*Total formula weight76507.4
*Water molecules are not included.

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PDB entries from 2026-01-14

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