8GF5

McrD binds asymmetrically to methyl-coenzyme M reductase improving active site accessibility during assembly

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Methyl-coenzyme M reductase subunit alpha	polymer	570	62180.1	2	UniProt (Q8THH1) Pfam (PF02745) Pfam (PF02249)	Methanosarcina acetivorans C2A	Coenzyme-B sulfoethylthiotransferase alpha
2	C, D (C, D)	Methyl-coenzyme M reductase subunit beta	polymer	434	45174.1	2	UniProt (Q8THG7) Pfam (PF02783) Pfam (PF02241)	Methanosarcina acetivorans C2A
3	E, F (E, F)	Methyl-coenzyme M reductase subunit gamma	polymer	248	27630.2	2	UniProt (Q8THH0) Pfam (PF02240)	Methanosarcina acetivorans C2A
4	G (X)	Methyl coenzyme M reductase, subunit D	polymer	193	21842.7	1	UniProt (Q8THG8) Pfam (PF02505)	Methanosarcina acetivorans C2A
5	H (A)	1-THIOETHANESULFONIC ACID	non-polymer		142.2	1	Chemie (COM)
6	I (A)	FACTOR 430	non-polymer		906.6	1	Chemie (F43)
7	J (B)	Coenzyme B	non-polymer		343.3	1	Chemie (TP7)

Sequence modifications

X: 1 - 170 (UniProt: Q8THG8)

PDB	External Database	Details
Met -22	-	expression tag
Asp -21	-	expression tag
Tyr -20	-	expression tag
Lys -19	-	expression tag
Asp -18	-	expression tag
Asp -17	-	expression tag
Asp -16	-	expression tag
Asp -15	-	expression tag
Lys -14	-	expression tag
Gly -13	-	expression tag
Gly -12	-	expression tag
Gly -11	-	expression tag
Trp -10	-	expression tag
Ser -9	-	expression tag
His -8	-	expression tag
Pro -7	-	expression tag
Gln -6	-	expression tag
Phe -5	-	expression tag
Glu -4	-	expression tag
Lys -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	291811.4
Non-Polymers*	Number of molecules	3
	Total formula weight	1392.1
All*	Total formula weight	293203.5

*Water molecules are not included.