8GDK
Crystal Structure of HIV-1 LM/HT CLADE A/E CRF01 GP120 Core in Complex with TFH-II-151
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | HIV-1 LM/HT Clade A/E CRF01 gp120 core | polymer | 355 | 39466.8 | 1 | UniProt (A0A0M3KKW9) Pfam (PF00516) In PDB | Human immunodeficiency virus 1 | |
2 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 13 | Chemie (NAG) | |||
3 | A | (3S,5R)-N-(4-chloro-3-fluorophenyl)-5-(hydroxymethyl)-1-[(3R,5S)-3,4,5-trimethylpiperazine-1-carbonyl]piperidine-3-carboxamide | non-polymer | 440.9 | 1 | Chemie (Z7N) | |||
4 | A | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
5 | A | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
6 | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A: 44 - 492 (UniProt: A0A0M3KKW9)
PDB | External Database | Details |
---|---|---|
Val 42 | - | expression tag |
Pro 43 | - | expression tag |
Tyr 61 | His 18 | engineered mutation |
His 105 | Gln 62 | engineered mutation |
Ile 108 | Val 65 | engineered mutation |
Thr 375 | His 242 | engineered mutation |
Asp 474 | Asn 335 | engineered mutation |
Met 475 | Ile 336 | engineered mutation |
Arg 476 | Lys 337 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 39466.8 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 3661.3 | |
All* | Total formula weight | 43128.1 |