8GD3
Crystal Structure of HIV-1 LM/HT Clade A/E CRF01 GP120 Core in Complex with DL-I-101
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | HIV-1 LM/HS clade A/E CRF01 gp120 core | polymer | 355 | 39452.7 | 1 | UniProt (A0A0M3KKW9) Pfam (PF00516) In PDB | Human immunodeficiency virus 1 | |
2 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) | |||
3 | A | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
4 | A | (3S,5R)-N-(4-chloro-3-fluorophenyl)-1-(4-glycylpiperazine-1-carbonyl)-5-(hydroxymethyl)piperidine-3-carboxamide | non-polymer | 455.9 | 1 | Chemie (Z1Z) | |||
5 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
6 | water | water | 18.0 | 64 | Chemie (HOH) |
Sequence modifications
A: 44 - 492 (UniProt: A0A0M3KKW9)
PDB | External Database | Details |
---|---|---|
Val 42 | - | expression tag |
Pro 43 | - | expression tag |
Tyr 61 | His 18 | engineered mutation |
His 105 | Gln 62 | engineered mutation |
Ile 108 | Val 65 | engineered mutation |
Ser 375 | His 242 | engineered mutation |
Asp 474 | Asn 335 | engineered mutation |
Met 475 | Ile 336 | engineered mutation |
Arg 476 | Lys 337 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 39452.7 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 3012.4 | |
All* | Total formula weight | 42465.1 |