8GC5

Domoate-bound GluK2 kainate receptors in non-active conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Glutamate receptor ionotropic, kainate 2	polymer	875	98883.5	4	UniProt (P42260) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus (Norway rat)	GluK2,Glutamate receptor 6,GluR-6,GluR6
2	E, G, H, I, L (E, G, H, I, L)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	5	In PDB GlyTouCan (G22768VO)
3	F, J (F, J)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
4	K (K)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
5	M, O, P, R, U... (A, B, C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)
6	N, Q, T, W (A, B, C, D)	(2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID	non-polymer		311.3	4	Chemie (DOQ)
7	S (C)	alpha-D-mannopyranose	non-polymer		180.2	1	Chemie (MAN)

Sequence modifications

A, B, C, D: 34 - 908 (UniProt: P42260)

PDB	External Database	Details
Val 567	Ile 567	conflict
Val 576	Cys 576	conflict
Ser 595	Cys 595	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	395533.9
Branched	Number of molecules	8
	Total formula weight	6151.6
Non-Polymers*	Number of molecules	11
	Total formula weight	2752.7
All*	Total formula weight	404438.2

*Water molecules are not included.