8GB8
Crystal structure of SARS-CoV-2 BA.2 receptor binding domain in complex with neutralizing antibody 20A7
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (E) | Spike protein S1 | polymer | 231 | 26261.7 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 | |
2 | B (H) | 20A7 Heavy chain | polymer | 224 | 23831.7 | 1 | Macaca mulatta (Rhesus monkey) | ||
3 | C (L) | 20A7 Light chain | polymer | 214 | 23201.7 | 1 | Macaca mulatta (Rhesus monkey) | ||
4 | D (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
5 | E, I, J (E, L) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
6 | F (L) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
7 | G (L) | GLYCINE | non-polymer | 75.1 | 1 | Chemie (GLY) | |||
8 | H (L) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
9 | K, L, M (E, H, L) | water | water | 18.0 | 194 | Chemie (HOH) |
Sequence modifications
E: 319 - 541 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Asp 339 | Gly 339 | variant |
Phe 371 | Ser 371 | variant |
Pro 373 | Ser 373 | variant |
Phe 375 | Ser 375 | variant |
Ala 376 | Thr 376 | variant |
Asn 405 | Asp 405 | variant |
Ser 408 | Arg 408 | variant |
Asn 417 | Lys 417 | variant |
Lys 440 | Asn 440 | variant |
Asn 477 | Ser 477 | variant |
Lys 478 | Thr 478 | variant |
Ala 484 | Glu 484 | variant |
Arg 493 | Gln 493 | variant |
Arg 498 | Gln 498 | variant |
Tyr 501 | Asn 501 | variant |
His 505 | Tyr 505 | variant |
Ser 542 | - | expression tag |
Gly 543 | - | expression tag |
His 544 | - | expression tag |
His 545 | - | expression tag |
His 546 | - | expression tag |
His 547 | - | expression tag |
His 548 | - | expression tag |
His 549 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 73295.1 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 680.7 | |
All* | Total formula weight | 73975.8 |