8GAU

Structure of human NDS.1 Fab and 1G01 Fab in complex with influenza virus neuraminidase from A/Indiana/10/2011 (H3N2v)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Vasodilator-stimulated phosphoprotein, Neuraminidase chimera	polymer	466	51799.1	1	UniProt (P50552) UniProt (G9LQ08) Pfam (PF08776) Pfam (PF00064)	Homo sapiens (human)	VASP
2	B (H)	Fab NDS.1, heavy chain	polymer	230	24597.7	1		Homo sapiens (human)
3	C (L)	Fab NDS.1, light chain	polymer	214	23357.0	1		Homo sapiens (human)
4	D (M)	Fab 1G01, heavy chain	polymer	240	25981.0	1		Homo sapiens (human)
5	E (N)	Fab 1G01, light chain	polymer	216	23677.3	1		Homo sapiens (human)
6	F (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

A: 32 - 70 (UniProt: P50552)

PDB	External Database	Details
Met 4	-	expression tag
Glu 5	-	expression tag
Phe 6	-	expression tag
Gly 7	-	expression tag
Leu 8	-	expression tag
Ser 9	-	expression tag
Trp 10	-	expression tag
Ile 11	-	expression tag
Phe 12	-	expression tag
Leu 13	-	expression tag
Ala 14	-	expression tag
Ala 15	-	expression tag
Ile 16	-	expression tag
Leu 17	-	expression tag
Lys 18	-	expression tag
Gly 19	-	expression tag
Val 20	-	expression tag
Gln 21	-	expression tag
Cys 22	-	expression tag
Ala 23	-	expression tag
Asp 24	-	expression tag
Pro 25	-	expression tag
His 26	-	expression tag
His 27	-	expression tag
His 28	-	expression tag
His 29	-	expression tag
His 30	-	expression tag
His 31	-	expression tag
Lys 71	-	linker
Arg 72	-	linker
Gly 73	-	linker
Ser 74	-	linker
Leu 75	-	linker
Val 76	-	linker
Pro 77	-	linker
Arg 78	-	linker
Gly 79	-	linker
Ser 80	-	linker
Gly 81	-	linker
Gly 82	-	linker

A: 83 - 469 (UniProt: G9LQ08)

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	149412.1
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	149633.3

*Water molecules are not included.