8GAS
vFP48.02 Fab in complex with BG505 DS-SOSIP Env trimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I (L, A, F) | vFP48.02 light chain | polymer | 112 | 12270.9 | 3 | Mus musculus (mouse) | ||
| 2 | B, F, J (H, C, I) | vFP48.02 heavy chain | polymer | 122 | 13383.9 | 3 | Mus musculus (mouse) | ||
| 3 | C, G, K (G, D, J) | Envelope glycoprotein gp120 | polymer | 481 | 54086.3 | 3 | UniProt (Q2N0S6) | Human immunodeficiency virus 1 (HIV-1) | |
| 4 | D, H, L (B, E, K) | Envelope glycoprotein gp41 | polymer | 153 | 17146.5 | 3 | UniProt (Q2N0S6) | Human immunodeficiency virus 1 (HIV-1) | |
| 5 | AA, EA, FA, M, Q... (a, e, f, M, Q...) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 9 | In PDB GlyTouCan (G15407YE) | |||
| 6 | BA, CA, DA, N, O... (b, c, d, N, O...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 9 | In PDB GlyTouCan (G42666HT) | |||
| 7 | GA, S, Z (g, S, Z) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) | |||
| 8 | AB, BB, CB, DB, EB... (D, E, J, G, K...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 36 | Chemie (NAG) |
Sequence modifications
G, D, J: 31 - 508 (UniProt: Q2N0S6)
B, E, K: 512 - 664 (UniProt: Q2N0S6)
| PDB | External Database | Details |
|---|---|---|
| Cys 201 | Ile 200 | conflict |
| Asn 332 | Thr 330 | conflict |
| Cys 433 | Ala 430 | conflict |
| Cys 501 | Ala 498 | conflict |
| Arg 509 | - | expression tag |
| Arg 510 | - | expression tag |
| Arg 511 | - | expression tag |
| Arg 512 | - | expression tag |
| Arg 513 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Pro 559 | Ile 556 | conflict |
| Cys 605 | Thr 602 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 290662.6 | |
| Branched | Number of molecules | 21 |
| Total formula weight | 11344.5 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 7963.5 | |
| All* | Total formula weight | 309970.7 |
