8G9V
Crystal structures of 17-beta-hydroxysteroid dehydrogenase 13
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | 17-beta-hydroxysteroid dehydrogenase 13 | polymer | 315 | 35502.3 | 8 | UniProt (Q7Z5P4) Pfam (PF00106) In PDB | Homo sapiens (human) | 17-beta-HSD 13,Short chain dehydrogenase/reductase family 16C member 3,Short-chain dehydrogenase/reductase 9 |
2 | E, F, A, G, B... | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 8 | Chemie (NAD) | |||
3 | E, F, A, G, B... | 4-{[2,5-dimethyl-3-(4-methylbenzene-1-sulfonyl)benzene-1-sulfonyl]amino}benzoic acid | non-polymer | 459.5 | 8 | Chemie (YYC) | |||
4 | D, E, A, C | O-DODECANYL OCTAETHYLENE GLYCOL | non-polymer | 538.8 | 4 | Chemie (CE1) | |||
5 | E, F, A, G, B... | SULFATE ION | non-polymer | 96.1 | 17 | Chemie (SO4) | |||
6 | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 2 - 300 (UniProt: Q7Z5P4)
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
Gly 1 | - | cloning artifact |
Lys 60 | Gln 60 | engineered mutation |
Arg 62 | Ile 62 | engineered mutation |
His 71 | Arg 71 | engineered mutation |
Lys 161 | Glu 161 | engineered mutation |
Gly 301 | - | expression tag |
Ser 302 | - | expression tag |
Gly 303 | - | expression tag |
His 304 | - | expression tag |
His 305 | - | expression tag |
His 306 | - | expression tag |
His 307 | - | expression tag |
His 308 | - | expression tag |
His 309 | - | expression tag |
His 310 | - | expression tag |
His 311 | - | expression tag |
His 312 | - | expression tag |
His 313 | - | expression tag |
His 314 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 284018.8 | |
Non-Polymers* | Number of molecules | 37 |
Total formula weight | 12771.8 | |
All* | Total formula weight | 296790.6 |