8G9T
Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | AcrIC9 | polymer | 70 | 8247.8 | 1 | UniProt (I3UM23) In PDB | Rhodobacter phage RcNL1 | |
| 2 | B, C, D, E, F... | Cas7 | polymer | 283 | 32208.1 | 7 | UniProt (A0A378VEU0) Pfam (PF05107) UniProt (by SIFTS) (D0W8X6) In PDB | Neisseria lactamica | |
| 3 | G, I, J, L | Cas11 | polymer | 124 | 14245.2 | 4 | UniProt (A0A378VF47) UniProt (by SIFTS) (D0W8X5) In PDB | Neisseria lactamica | |
| 4 | K | Cas8 | polymer | 582 | 64860.8 | 1 | UniProt (A0A378VF47) Pfam (PF09709) UniProt (by SIFTS) (D0W8X5) In PDB | Neisseria lactamica | |
| 5 | N | Cas5 | polymer | 205 | 23870.5 | 1 | UniProt (D0W8X4) Pfam (PF09704) In PDB | Neisseria lactamica | |
| 6 | O | crRNA (43-MER) | polymer | 43 | 13870.3 | 1 | Neisseria lactamica |
Sequence modifications
B, C, D, E, F, H, M: 2 - 283 (UniProt: A0A378VEU0)
K: 1 - 582 (UniProt: A0A378VF47)
| PDB | External Database | Details |
|---|---|---|
| Gly 284 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 190 | Val 190 | conflict |
| Ala 239 | Ile 239 | conflict |
| Ile 242 | Val 242 | conflict |
| Gly 260 | Ser 260 | conflict |
| Thr 271 | Ala 271 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 393286.9 | |
| All* | Total formula weight | 393286.9 |
