8G9C
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with 5- difluoromethylenebisphosphonate inositol pentakisphosphate (5-PCF2P-IP5), an analogue of 5-InsP7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Diphosphoinositol polyphosphate phosphohydrolase 1 | polymer | 172 | 19497.0 | 1 | UniProt (O95989) Pfam (PF00293) | Homo sapiens (human) | DIPP-1,Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1,Nucleoside diphosphate-linked moiety X motif 3,Nudix motif 3 |
| 2 | B (A) | {difluoro[(R)-hydroxy{[(1s,2R,3S,4S,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]oxy}phosphoryl]methyl}phosphonic acid | non-polymer | 774.0 | 1 | Chemie (YUT) | |||
| 3 | C, D, E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | G, H (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | I (A) | FLUORIDE ION | non-polymer | 19.0 | 1 | Chemie (F) | |||
| 6 | J (A) | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19497.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 961.1 | |
| All* | Total formula weight | 20458.1 |
