8G8H
Crystal structure of human DNA polymerase eta incorporating ITP across dC
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase eta | polymer | 432 | 48325.4 | 1 | UniProt (Q9Y253) Pfam (PF00817) Pfam (PF21704) Pfam (PF11799) | Homo sapiens (human) | RAD30 homolog A,Xeroderma pigmentosum variant type protein |
| 2 | B (T) | DNA (5'-D(P*AP*TP*CP*CP*TP*CP*AP*CP*GP*CP*T)-3') | polymer | 12 | 3542.3 | 1 | Homo sapiens | ||
| 3 | C (P) | DNA (5'-D(*AP*GP*CP*GP*TP*GP*AP*G)-3') | polymer | 8 | 2506.7 | 1 | Homo sapiens | ||
| 4 | D (A) | [[(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-(6-oxidanylidene-1~{H}-purin-9-yl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | non-polymer | 508.2 | 1 | Chemie (CZU) | |||
| 5 | E (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | F, G, H (A, T, P) | water | water | 18.0 | 311 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 54374.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 548.2 | |
| All* | Total formula weight | 54922.6 |
