8G8H
Crystal structure of human DNA polymerase eta incorporating ITP across dC
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase eta | polymer | 432 | 48325.4 | 1 | UniProt (Q9Y253) Pfam (PF00817) Pfam (PF21704) Pfam (PF11799) | Homo sapiens (human) | RAD30 homolog A,Xeroderma pigmentosum variant type protein |
| 2 | B (T) | DNA (5'-D(P*AP*TP*CP*CP*TP*CP*AP*CP*GP*CP*T)-3') | polymer | 12 | 3542.3 | 1 | Homo sapiens | ||
| 3 | C (P) | DNA (5'-D(*AP*GP*CP*GP*TP*GP*AP*G)-3') | polymer | 8 | 2506.7 | 1 | Homo sapiens | ||
| 4 | D (A) | [[(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-(6-oxidanylidene-1~{H}-purin-9-yl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | non-polymer | 508.2 | 1 | Chemie (CZU) PubChem (135475338) PubChem (135699675) PubChem (137247150) PubChem (135398643) PubChem (135402038) PubChem (135870597) PubChem (135887989) PubChem (135887990) PubChem (135976326) PubChem (136053443) PubChem (136162270) PubChem (136401383) PubChem (136401386) PubChem (136401388) PubChem (136663953) PubChem (136664746) PubChem (136826005) PubChem (137090202) PubChem (138454309) PubChem (163603984) PubChem (171699531) | |||
| 5 | E (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) PubChem (271) | |||
| 6 | F, G, H (A, T, P) | water | water | 18.0 | 311 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 54374.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 548.2 | |
| All* | Total formula weight | 54922.6 |
