8G7U
Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-semi-closed end)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Antiviral innate immune response receptor RIG-I | polymer | 925 | 106740.6 | 2 | UniProt (O95786) Pfam (PF16739) Pfam (PF00270) Pfam (PF18119) Pfam (PF00271) Pfam (PF11648) | Homo sapiens (human) | DEAD box protein 58,Probable ATP-dependent RNA helicase DDX58,RIG-I-like receptor 1,RLR-1,Retinoic acid-inducible gene 1 protein,RIG-1,Retinoic acid-inducible gene I protein,RIG-I |
| 2 | B, D (B, D) | E3 ubiquitin-protein ligase RNF135 | polymer | 432 | 47946.3 | 2 | UniProt (Q8IUD6) Pfam (PF15227) Pfam (PF00622) | Homo sapiens (human) | RIG-I E3 ubiquitin ligase,REUL,RING finger protein 135,RING finger protein leading to RIG-I activation,Riplet,RING-type E3 ubiquitin transferase RNF135 |
| 3 | E (X) | p3dsRNA24a | polymer | 24 | 7885.6 | 1 | Homo sapiens | ||
| 4 | F (Y) | p3dsRNA24b | polymer | 24 | 7788.6 | 1 | Homo sapiens | ||
| 5 | G, H (A, C) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 325047.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 325178.7 |
