8G6A
Wildtype PTP1b in complex with DES6016
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Tyrosine-protein phosphatase non-receptor type 1 | polymer | 298 | 34720.6 | 2 | UniProt (P18031) Pfam (PF00102) In PDB | Homo sapiens (human) | Protein-tyrosine phosphatase 1B,PTP-1B |
| 2 | A | {(2S)-4-[6-methyl-2-(trifluoromethyl)quinolin-4-yl]piperazin-2-yl}methanol | non-polymer | 325.3 | 1 | Chemie (ZD3) | |||
| 3 | A | {(2R)-4-[6-methyl-2-(trifluoromethyl)quinolin-4-yl]piperazin-2-yl}methanol | non-polymer | 325.3 | 1 | Chemie (ZD5) | |||
| 4 | A | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 5 | B | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | B | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 7 | water | water | 18.0 | 365 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69441.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 903.3 | |
| All* | Total formula weight | 70344.4 |
