8G65
Wildtype PTP1b in complex with DES4799
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tyrosine-protein phosphatase non-receptor type 1 | polymer | 298 | 34720.6 | 2 | UniProt (P18031) Pfam (PF00102) | Homo sapiens (human) | Protein-tyrosine phosphatase 1B,PTP-1B |
| 2 | C, D (A, B) | 4-(3,5-dimethyl-1H-pyrazol-1-yl)aniline | non-polymer | 187.2 | 2 | Chemie (YW9) | |||
| 3 | E (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | F (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | G (B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | H, I (A, B) | water | water | 18.0 | 642 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69441.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 512.4 | |
| All* | Total formula weight | 69953.5 |
