8G4L
Cryo-EM structure of the human cardiac myosin filament
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, AB, AD, B, BB... (BB, BA, BG, BH, BI...) | Myosin-7 | polymer | 1935 | 223446.0 | 78 | UniProt (P12883) Pfam (PF02736) Pfam (PF00063) Pfam (PF01576) | Homo sapiens (human) | Myosin heavy chain 7,Myosin heavy chain slow isoform,MyHC-slow,Myosin heavy chain,cardiac muscle beta isoform,MyHC-beta |
| 2 | C, CD, D, DD, EA... (BE, BF, ba, bb, bg...) | Myosin light chain 3 | polymer | 195 | 21962.1 | 18 | UniProt (P08590) | Homo sapiens (human) | Cardiac myosin light chain 1,CMLC1,Myosin light chain 1,slow-twitch muscle B/ventricular isoform,MLC1SB,Ventricular myosin alkali light chain,Ventricular myosin light chain 1,VLCl,Ventricular/slow twitch myosin alkali light chain,MLC-lV/sb, Essential light chain |
| 3 | AA, BA, CC, DC, ED... (bc, bd, bi, bj, bq...) | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform | polymer | 166 | 18813.3 | 18 | UniProt (P10916) Pfam (PF13499) | Homo sapiens (human) | MLC-2v,Cardiac myosin light chain 2,Myosin light chain 2,slow skeletal/ventricular muscle isoform,MLC-2s/v,Ventricular myosin light chain 2 |
| 4 | AC, KA, LA, OD, PD... (bm, bn, am, an, m...) | Titin | polymer | 1084 | 119772.0 | 6 | UniProt (Q8WZ42) Pfam (PF00041) Pfam (PF07679) | Homo sapiens (human) | Connectin,Rhabdomyosarcoma antigen MU-RMS-40.14 |
| 5 | BC, MA, QD (bo, ao, o) | Myosin-binding protein C, cardiac-type | polymer | 1274 | 140947.2 | 3 | UniProt (Q14896) Pfam (PF07679) Pfam (PF18362) Pfam (PF00041) | Homo sapiens (human) | Cardiac MyBP-C,C-protein,cardiac muscle isoform |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 123 |
| Total formula weight | 19304216.2 | |
| All* | Total formula weight | 19304216.2 |
