8G3X
MBP-Mcl1 in complex with ligand 32
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Maltodextrin-binding protein, Induced myeloid leukemia cell differentiation protein Mcl-1 chimera | polymer | 518 | 57310.9 | 1 | UniProt (A0A4P1LXE0) UniProt (Q07820) Pfam (PF00452) | Serratia sp. FS14 | Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
| 2 | B (R) | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900001) GlyTouCan (G07411ON) | |||
| 3 | C, D, E, F, G... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 10 | Chemie (EDO) | |||
| 4 | M (A) | N-[(1'S,3aS,5R,15S,17S,19Z,21R,21aR)-6'-chloro-20-fluoro-21-{[(5S,9aS)-hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]methyl}-21-methoxy-17-methyl-13,15-dioxo-2,3,3',3a,4,4',13,16,17,18,21,21a-dodecahydro-2'H,6H,8H-15lambda~6~-spiro[10,12-(ethanediylidene)-15lambda~6~-furo[3,2-i][1,4]oxazepino[3,4-f][1,2,7]thiadiazacyclohexadecine-7,1'-naphthalen]-15-yl]-3-methoxy-1-methyl-1H-pyrazole-4-carboxamide | non-polymer | 924.5 | 1 | Chemie (YLF) | |||
| 5 | N (A) | water | water | 18.0 | 557 | Chemie (HOH) |
Sequence modifications
A: -196 - 170 (UniProt: A0A4P1LXE0)
A: 173 - 321 (UniProt: Q07820)
| PDB | External Database | Details |
|---|---|---|
| Gly 171 | - | linker |
| Ser 172 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ala 194 | Lys 194 | conflict |
| Ala 197 | Lys 197 | conflict |
| Ala 201 | Arg 201 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 57310.9 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1545.2 | |
| All* | Total formula weight | 59198.4 |
