8G3W
MBP-Mcl1 in complex with ligand 28
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Maltodextrin-binding protein, Induced myeloid leukemia cell differentiation protein Mcl-1 chimera | polymer | 518 | 57310.9 | 1 | UniProt (A0A4P1LXE0) UniProt (Q07820) Pfam (PF00452) In PDB | Serratia sp. FS14 | Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
2 | R | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900001) GlyTouCan (G07411ON) | |||
3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
4 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
5 | A | N-[(1'S,3aS,5R,15S,17S,19Z,21R,21aR)-6'-chloro-20-fluoro-21-methoxy-17-methyl-13,15-dioxo-2,3,3',3a,4,4',13,16,17,18,21,21a-dodecahydro-2'H,6H,8H-15lambda~6~-spiro[10,12-(ethanediylidene)-15lambda~6~-furo[3,2-i][1,4]oxazepino[3,4-f][1,2,7]thiadiazacyclohexadecine-7,1'-naphthalen]-15-yl]-3-methoxy-1-methyl-1H-pyrazole-4-carboxamide | non-polymer | 770.3 | 1 | Chemie (YKX) | |||
6 | water | water | 18.0 | 449 | Chemie (HOH) |
Sequence modifications
A: -196 - 170 (UniProt: A0A4P1LXE0)
A: 173 - 321 (UniProt: Q07820)
PDB | External Database | Details |
---|---|---|
Gly 171 | - | linker |
Ser 172 | - | linker |
PDB | External Database | Details |
---|---|---|
Ala 194 | Lys 194 | conflict |
Ala 197 | Lys 197 | conflict |
Ala 201 | Arg 201 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 57310.9 | |
Branched | Number of molecules | 1 |
Total formula weight | 342.3 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1062.6 | |
All* | Total formula weight | 58715.8 |