8G2M
The tumor activated anti-CTLA-4 monoclonal antibody XTX101 demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | F | masking peptide | polymer | 9 | 992.2 | 1 | Peptide display vector fth1 | ||
| 2 | H | Heavy chain of humanized IgG | polymer | 220 | 23624.6 | 1 | Mus musculus | ||
| 3 | L | Light chain of humanized IgG | polymer | 202 | 22294.5 | 1 | Mus musculus | ||
| 4 | L | CITRIC ACID | non-polymer | 192.1 | 1 | Chemie (CIT) | |||
| 5 | water | water | 18.0 | 541 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 46911.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 47103.5 |
