8G0P
Crystal structure of the human Ndc80:Nuf2 loop region
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Kinetochore protein NDC80 homolog | polymer | 143 | 16652.0 | 1 | UniProt (O14777) Pfam (PF24487) | Homo sapiens (human) | Highly expressed in cancer protein,Kinetochore protein Hec1,HsHec1,Kinetochore-associated protein 2,Retinoblastoma-associated protein HEC |
| 2 | B (B) | Kinetochore protein Nuf2 | polymer | 98 | 11567.3 | 1 | UniProt (Q9BZD4) | Homo sapiens (human) | hNuf2,hNuf2R,hsNuf2,Cell division cycle-associated protein 1 |
| 3 | C, D (A, B) | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
A: 3 - 142 (UniProt: O14777)
B: 2 - 97 (UniProt: Q9BZD4)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Cys 2 | - | expression tag |
| Cys 143 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Cys 1 | - | expression tag |
| Cys 98 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28219.3 | |
| All* | Total formula weight | 28219.3 |
