8G0G
Crystal structure of diphtheria toxin H223Q/H257Q double mutant (pH 4.5)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Diphtheria toxin | polymer | 538 | 58724.8 | 2 | UniProt (Q5PY51) Pfam (PF02763) Pfam (PF02764) Pfam (PF01324) | Corynebacterium diphtheriae | |
| 2 | C, D (A, B) | ADENYLYL-3'-5'-PHOSPHO-URIDINE-3'-MONOPHOSPHATE | non-polymer | 653.4 | 2 | Chemie (APU) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 280 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 535 (UniProt: Q5PY51)
| PDB | External Database | Details |
|---|---|---|
| Glu 51 | Lys 52 | engineered mutation |
| Lys 148 | Glu 149 | engineered mutation |
| Gln 223 | His 224 | engineered mutation |
| Gln 257 | His 258 | engineered mutation |
| Met 536 | - | expression tag |
| Ala 537 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 117449.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1306.8 | |
| All* | Total formula weight | 118756.4 |
