8FZ6
The human PI31 complexed with bovine 20S proteasome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, O (A, O) | Proteasome subunit alpha type-6 | polymer | 246 | 27432.5 | 2 | UniProt (Q2YDE4) Pfam (PF10584) Pfam (PF00227) | Bos taurus (cattle) | |
| 2 | B, P (B, P) | Proteasome subunit alpha type-2 | polymer | 234 | 25927.5 | 2 | UniProt (Q3T0Y5) Pfam (PF10584) Pfam (PF00227) | Bos taurus (cattle) | |
| 3 | C, Q (C, Q) | Proteasome subunit alpha type-4 | polymer | 261 | 29525.8 | 2 | UniProt (Q3ZCK9) Pfam (PF10584) Pfam (PF00227) | Bos taurus (cattle) | |
| 4 | D, R (D, R) | Proteasome subunit alpha type-7 | polymer | 248 | 27911.9 | 2 | UniProt (Q3ZBG0) Pfam (PF10584) Pfam (PF00227) | Bos taurus (cattle) | |
| 5 | E, S (E, S) | Proteasome subunit alpha type-5 | polymer | 241 | 26436.0 | 2 | UniProt (Q5E987) Pfam (PF00227) Pfam (PF10584) | Bos taurus (cattle) | |
| 6 | F, T (F, T) | Proteasome subunit alpha type-1 | polymer | 263 | 29625.7 | 2 | UniProt (Q3T0X5) Pfam (PF10584) Pfam (PF00227) | Bos taurus (cattle) | |
| 7 | G, U (G, U) | Proteasome subunit alpha type-3 | polymer | 255 | 28441.2 | 2 | UniProt (Q58DU5) Pfam (PF10584) Pfam (PF00227) | Bos taurus (cattle) | |
| 8 | H, V (H, V) | Proteasome subunit beta type-6 | polymer | 239 | 25563.0 | 2 | UniProt (Q3MHN0) Pfam (PF00227) | Bos taurus (cattle) | |
| 9 | I, W (I, W) | Proteasome subunit beta type-7 | polymer | 277 | 30045.4 | 2 | UniProt (Q2TBP0) Pfam (PF00227) Pfam (PF12465) | Bos taurus (cattle) | |
| 10 | J, X (J, X) | Proteasome subunit beta type-3 | polymer | 205 | 23016.9 | 2 | UniProt (P33672) Pfam (PF00227) | Bos taurus (cattle) | Proteasome chain 13,Proteasome component C10-II,Proteasome theta chain |
| 11 | K, Y (K, Y) | Proteasome subunit beta type-2 | polymer | 201 | 22924.3 | 2 | UniProt (Q5E9K0) Pfam (PF00227) | Bos taurus (cattle) | |
| 12 | L, Z (L, Z) | Proteasome subunit beta type-5 | polymer | 263 | 28642.3 | 2 | UniProt (Q32KL2) Pfam (PF00227) | Bos taurus (cattle) | |
| 13 | AA, M (M, a) | Proteasome subunit beta type-1 | polymer | 241 | 26278.1 | 2 | UniProt (Q2TBX6) Pfam (PF00227) | Bos taurus (cattle) | |
| 14 | BA, N (N, b) | Proteasome subunit beta type-4 | polymer | 264 | 29057.0 | 2 | UniProt (Q3T108) Pfam (PF00227) | Bos taurus (cattle) | |
| 15 | CA, DA (c, d) | Proteasome inhibitor PI31 subunit | polymer | 271 | 29850.7 | 2 | UniProt (Q3SX30) Pfam (PF11566) Pfam (PF08577) | Bos taurus (cattle) |
Sequence modifications
c, d: 1 - 271 (UniProt: Q3SX30)
| PDB | External Database | Details |
|---|---|---|
| Arg 18 | Ala 18 | conflict |
| Phe 36 | Tyr 36 | conflict |
| Val 40 | Ala 40 | conflict |
| Ala 56 | Val 56 | conflict |
| Gly 57 | Glu 57 | conflict |
| Asn 60 | Ser 60 | conflict |
| Tyr 71 | Ser 71 | conflict |
| Ile 83 | Val 83 | conflict |
| Ser 87 | Asn 87 | conflict |
| Leu 91 | Ile 91 | conflict |
| Tyr 96 | His 96 | conflict |
| Ala 102 | Ser 102 | conflict |
| Asp 109 | Asn 109 | conflict |
| Ala 114 | Ser 114 | conflict |
| Gly 118 | Val 118 | conflict |
| Thr 123 | Val 123 | conflict |
| Val 151 | - | insertion |
| Ser 152 | Leu 151 | conflict |
| Pro 172 | His 171 | conflict |
| His 174 | Gln 173 | conflict |
| Pro 183 | Thr 182 | conflict |
| Val 192 | Ala 191 | conflict |
| Pro 203 | Cys 202 | conflict |
| Pro 254 | Ser 253 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 30 |
| Total formula weight | 821356.6 | |
| All* | Total formula weight | 821356.6 |
