8FYI
Structure of HIV-1 BG505 SOSIP-HT1 in complex with one CD4 molecule
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Envelope glycoprotein gp160 | polymer | 474 | 53193.2 | 1 | UniProt (Q2N0S5) Pfam (PF00516) | Human immunodeficiency virus 1 | Env polyprotein |
| 2 | B, C (B, C) | Envelope glycoprotein gp160 | polymer | 474 | 53235.4 | 2 | UniProt (Q2N0S5) Pfam (PF00516) | Human immunodeficiency virus 1 | Env polyprotein |
| 3 | D, E, F (D, E, F) | Envelope glycoprotein gp41 | polymer | 128 | 14577.6 | 3 | Human immunodeficiency virus 1 | ||
| 4 | G (Z) | T-cell surface glycoprotein CD4 | polymer | 379 | 42325.5 | 1 | UniProt (P01730) Pfam (PF00047) Pfam (PF05790) Pfam (PF09191) | Homo sapiens (human) | T-cell surface antigen T4/Leu-3 |
| 5 | H, K, M, N, P (G, J, L, M, O) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 5 | In PDB GlyTouCan (G42666HT) | |||
| 6 | I, L (H, K) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 383.3 | 2 | In PDB GlyTouCan (G90333CG) | |||
| 7 | J (I) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(6-8)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 830.8 | 1 | In PDB | |||
| 8 | O (N) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 9 | AA, BA, CA, DA, EA... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 35 | Chemie (NAG) |
Sequence modifications
A: 33 - 508 (UniProt: Q2N0S5)
B, C: 33 - 508 (UniProt: Q2N0S5)
Z: 1 - 371 (UniProt: P01730)
| PDB | External Database | Details |
|---|---|---|
| Trp 316 | Ala 313 | conflict |
| Asn 332 | Thr 330 | conflict |
| Cys 501 | Ala 498 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Trp 316 | Ala 313 | conflict |
| Asn 332 | Thr 330 | conflict |
| Arg 368 | Asp 366 | engineered mutation |
| Cys 501 | Ala 498 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 372 | - | expression tag |
| Ser 373 | - | expression tag |
| His 374 | - | expression tag |
| His 375 | - | expression tag |
| His 376 | - | expression tag |
| His 377 | - | expression tag |
| His 378 | - | expression tag |
| His 379 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 245722.2 | |
| Branched | Number of molecules | 9 |
| Total formula weight | 4306.0 | |
| Non-Polymers* | Number of molecules | 35 |
| Total formula weight | 7742.3 | |
| All* | Total formula weight | 257770.5 |
