Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

8FYE

4-F, 5-MeO-PyrT-bound serotonin 1A (5-HT1A) receptor-Gi1 protein complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Guanine nucleotide-binding protein G(i) subunit alpha-1polymer35440415.01UniProt (P63096)
Pfam (PF00503)
Homo sapiens (human)Adenylate cyclase-inhibiting G alpha protein
2B
(B)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1polymer35839418.11UniProt (P62873)
Pfam (PF00400)
Homo sapiens (human)Transducin beta chain 1
3C
(G)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2polymer808506.81UniProt (P59768)
Pfam (PF00631)
Homo sapiens (human)G gamma-I
4D
(R)
Soluble cytochrome b562,5-hydroxytryptamine receptor 1A,5-hydroxytryptamine receptor 1Apolymer55261375.91UniProt (P08908)
Pfam (PF07361)
Pfam (PF00001)
UniProt (by SIFTS) (P0ABE7)
Homo sapiens (human)5-HT-1A,5-HT1A,G-21,Serotonin receptor 1A
5E
(R)
4-fluoro-5-methoxy-3-[2-(pyrrolidin-1-yl)ethyl]-1H-indolenon-polymer262.31Chemie (YGH)
6F
(R)
[(2R)-1-[oxidanyl-[(2R,3R,5S,6R)-2,3,5,6-tetrakis(oxidanyl)-4-phosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-3-tetradecanoyloxy-propan-2-yl] (5E,8E)-hexadeca-5,8,11,14-tetraenoatenon-polymer854.91Chemie (J40)
7G, H
(R)
CHOLESTEROL HEMISUCCINATEnon-polymer486.72Chemie (Y01)
Sequence modifications
B: 2 - 340 (UniProt: P62873)
PDBExternal DatabaseDetails
Met -17-expression tag
His -16-expression tag
His -15-expression tag
His -14-expression tag
His -13-expression tag
His -12-expression tag
His -11-expression tag
Leu -10-expression tag
Glu -9-expression tag
Val -8-expression tag
Leu -7-expression tag
Phe -6-expression tag
Gln -5-expression tag
Gly -4-expression tag
Pro -3-expression tag
Gly -2-expression tag
Ser -1-expression tag
Ser 0-expression tag
Gly 1-expression tag
G: 1 - 71 (UniProt: P59768)
PDBExternal DatabaseDetails
Gly 72-expression tag
Ser 73-expression tag
Ala 74-expression tag
Gly 75-expression tag
Ser 76-expression tag
Ala 77-expression tag
Gly 78-expression tag
Ser 79-expression tag
Ala 80-expression tag
R: -129 - 25 (PDB: 8FYE)
R: 26 - 422 (UniProt: P08908)
PDBExternal DatabaseDetails
Trp 125Leu 125engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight149715.8
Non-Polymers*Number of molecules4
Total formula weight2090.7
All*Total formula weight151806.5
*Water molecules are not included.

227111

PDB entries from 2024-11-06

PDB statisticsPDBj update infoContact PDBjnumon