8FX3
Crystal structure of the Trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRT), isoform D, bound to Immucillin-GP, showing the structure of the complete active site in its open conformation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Hypoxanthine-guanine phosphoribosyltransferase | polymer | 231 | 25883.0 | 2 | UniProt (A0A7J6XZA2) Pfam (PF00156) UniProt (by SIFTS) (Q4DGA2) In PDB | Trypanosoma cruzi (strain CL Brener) | |
2 | A, B | PHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN-2-YLMETHYL] ESTER | non-polymer | 361.2 | 2 | Chemie (IMU) | |||
3 | water | water | 18.0 | 308 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 51766.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 722.5 | |
All* | Total formula weight | 52488.5 |