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8FX2

Crystal structure of the Trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRT), isoform D, bound to Immucillin-HP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Hypoxanthine-guanine phosphoribosyltransferasepolymer23125883.02UniProt (A0A7J6XZA2)
Pfam (PF00156)
UniProt (by SIFTS) (Q4DGA2)
Trypanosoma cruzi (strain CL Brener)
2C, D
(A, B)
(1S)-1(9-DEAZAHYPOXANTHIN-9YL)1,4-DIDEOXY-1,4-IMINO-D-RIBITOL-5-PHOSPHATEnon-polymer346.22Chemie (IRP)
3E, F
(A, B)
waterwater18.0317Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight51766.0
Non-Polymers*Number of molecules2
Total formula weight692.5
All*Total formula weight52458.4
*Water molecules are not included.

238895

PDB entries from 2025-07-16

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