8FX1
Crystal structure of the Trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRT), isoform D, bound to (R)-SerMe-ImmH Phosphonate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | Hypoxanthine-guanine phosphoribosyltransferase | polymer | 231 | 25883.0 | 2 | UniProt (A0A7J6XZA2) Pfam (PF00156) UniProt (by SIFTS) (Q4DGA2) | Trypanosoma cruzi (strain CL Brener) | |
2 | C, D (A, B) | [(3R)-4-hydroxy-3-{[(4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}butyl]phosphonic acid | non-polymer | 316.3 | 2 | Chemie (YC9) | |||
3 | E, F (A, B) | water | water | 18.0 | 131 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 51766.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 632.5 | |
All* | Total formula weight | 52398.5 |