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8FWZ

Crystal structure of the Trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRT), isoform D, bound to Hydroxypropyl-Lin-ImmH Phosphonate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BHypoxanthine-guanine phosphoribosyltransferasepolymer23125883.02UniProt (A0A7J6XZA2)
Pfam (PF00156)
UniProt (by SIFTS) (Q4DGA2)
In PDB
Trypanosoma cruzi (strain CL Brener)
2A, B[(2R)-2-hydroxy-3-{[(4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}propyl]phosphonic acidnon-polymer302.22Chemie (YCE)
3APHOSPHATE IONnon-polymer95.01Chemie (PO4)
4waterwater18.0178Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight51766.0
Non-Polymers*Number of molecules3
Total formula weight699.4
All*Total formula weight52465.4
*Water molecules are not included.

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PDB entries from 2024-09-11

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