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8FV2

Bromodomain of CBP liganded with CCS-1477

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
CREB-binding proteinpolymer11613847.94UniProt (Q92793)
Pfam (PF00439)
Homo sapiens (human)Histone lysine acetyltransferase CREBBP,Protein-lysine acetyltransferase CREBBP
2E, G, H, I, J
(A, B)
PHOSPHATE IONnon-polymer95.05Chemie (PO4)
3F, L, M, N, O...
(A, B, C, D)
(6S)-1-[3,4-bis(fluoranyl)phenyl]-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(4-methoxycyclohexyl)benzimidazol-2-yl]piperidin-2-onenon-polymer534.66Chemie (JHL)
4K, Q
(B, D)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
5R, S, T, U
(A, B, C, D)
waterwater18.0463Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight55391.5
Non-Polymers*Number of molecules13
Total formula weight3806.6
All*Total formula weight59198.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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