8FS3
Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 1 (open 9-1-1 and shoulder bound DNA only)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Checkpoint protein RAD24 | polymer | 545 | 62792.5 | 1 | UniProt (P32641) Pfam (PF03215) In PDB | Saccharomyces cerevisiae (baker's yeast) | |
| 2 | B | Replication factor C subunit 4 | polymer | 323 | 36201.0 | 1 | UniProt (P40339) Pfam (PF00004) Pfam (PF08542) In PDB | Saccharomyces cerevisiae (baker's yeast) | Replication factor C4,Activator 1 37 kDa subunit |
| 3 | C | Replication factor C subunit 3 | polymer | 336 | 37841.1 | 1 | UniProt (P38629) Pfam (PF00004) Pfam (PF08542) In PDB | Saccharomyces cerevisiae (baker's yeast) | Replication factor C3,Activator 1 40 kDa subunit |
| 4 | D | Replication factor C subunit 2 | polymer | 353 | 39794.5 | 1 | UniProt (P40348) Pfam (PF00004) Pfam (PF21960) Pfam (PF08542) In PDB | Saccharomyces cerevisiae (baker's yeast) | Replication factor C2,Activator 1 41 kDa subunit |
| 5 | E | Replication factor C subunit 5 | polymer | 354 | 39993.6 | 1 | UniProt (P38251) Pfam (PF21960) Pfam (PF22534) Pfam (PF13177) In PDB | Saccharomyces cerevisiae (baker's yeast) | Replication factor C5,Activator 1 40 kDa subunit |
| 6 | F | DNA damage checkpoint control protein MEC3 | polymer | 474 | 53207.8 | 1 | UniProt (Q02574) Pfam (PF04005) In PDB | Saccharomyces cerevisiae (baker's yeast) | |
| 7 | G | DNA damage checkpoint control protein RAD17 | polymer | 401 | 45637.5 | 1 | UniProt (A0A8H4BW58) Pfam (PF02144) UniProt (by SIFTS) (P48581) In PDB | Saccharomyces cerevisiae (baker's yeast) | |
| 8 | H | DDC1 isoform 1 | polymer | 612 | 69787.5 | 1 | UniProt (A0A8H4BUG7) UniProt (by SIFTS) (Q08949) In PDB | Saccharomyces cerevisiae (baker's yeast) | |
| 9 | I | Template strand | polymer | 50 | 15389.9 | 1 | synthetic construct | ||
| 10 | K | Primer strand 2 | polymer | 20 | 6084.9 | 1 | synthetic construct | ||
| 11 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 12 | A, B, C, D | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | non-polymer | 523.2 | 4 | Chemie (AGS) | |||
| 13 | E | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 406730.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2617.4 | |
| All* | Total formula weight | 409347.7 |
