8FRW
Full-length mouse 5-HT3A receptor in complex with ALB148471, pre-activated
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | 5-hydroxytryptamine receptor 3A | polymer | 553 | 62349.8 | 5 | UniProt (E9QLC0) Pfam (PF02931) Pfam (PF02932) UniProt (by SIFTS) (P23979) | Mus musculus (house mouse) | |
| 2 | F, G, H, K, L... (A, B, C, D, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 15 | Chemie (NAG) | |||
| 3 | I, J, N, R, V (A, B, C, D, E) | 5-[(1R,3S,5R)-1-azabicyclo[3.2.2]nonan-3-yl]-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indazol-6-one | non-polymer | 310.4 | 5 | Chemie (Y7H) | |||
| 4 | AA, BA, CA, DA, Z (B, C, D, E, A) | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 462 (UniProt: E9QLC0)
| PDB | External Database | Details |
|---|---|---|
| Trp -74 | - | expression tag |
| Ser -73 | - | expression tag |
| His -72 | - | expression tag |
| Pro -71 | - | expression tag |
| Gln -70 | - | expression tag |
| Phe -69 | - | expression tag |
| Glu -68 | - | expression tag |
| Lys -67 | - | expression tag |
| Gly -66 | - | expression tag |
| Gly -65 | - | expression tag |
| Gly -64 | - | expression tag |
| Ser -63 | - | expression tag |
| Gly -62 | - | expression tag |
| Gly -61 | - | expression tag |
| Gly -60 | - | expression tag |
| Ser -59 | - | expression tag |
| Gly -58 | - | expression tag |
| Gly -57 | - | expression tag |
| Gly -56 | - | expression tag |
| Ser -55 | - | expression tag |
| Trp -54 | - | expression tag |
| Ser -53 | - | expression tag |
| His -52 | - | expression tag |
| Pro -51 | - | expression tag |
| Gln -50 | - | expression tag |
| Phe -49 | - | expression tag |
| Glu -48 | - | expression tag |
| Lys -47 | - | expression tag |
| Gly -46 | - | expression tag |
| Gly -45 | - | expression tag |
| Gly -44 | - | expression tag |
| Ser -43 | - | expression tag |
| Gly -42 | - | expression tag |
| Gly -41 | - | expression tag |
| Gly -40 | - | expression tag |
| Ser -39 | - | expression tag |
| Gly -38 | - | expression tag |
| Gly -37 | - | expression tag |
| Gly -36 | - | expression tag |
| Ser -35 | - | expression tag |
| Trp -34 | - | expression tag |
| Ser -33 | - | expression tag |
| His -32 | - | expression tag |
| Pro -31 | - | expression tag |
| Gln -30 | - | expression tag |
| Phe -29 | - | expression tag |
| Glu -28 | - | expression tag |
| Lys -27 | - | expression tag |
| Gly -26 | - | expression tag |
| Gly -25 | - | expression tag |
| Gly -24 | - | expression tag |
| Ser -23 | - | expression tag |
| Gly -22 | - | expression tag |
| Gly -21 | - | expression tag |
| Gly -20 | - | expression tag |
| Ser -19 | - | expression tag |
| Gly -18 | - | expression tag |
| Gly -17 | - | expression tag |
| Gly -16 | - | expression tag |
| Ser -15 | - | expression tag |
| Trp -14 | - | expression tag |
| Ser -13 | - | expression tag |
| His -12 | - | expression tag |
| Pro -11 | - | expression tag |
| Gln -10 | - | expression tag |
| Phe -9 | - | expression tag |
| Glu -8 | - | expression tag |
| Lys -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Glu 463 | - | expression tag |
| Asn 464 | - | expression tag |
| Leu 465 | - | expression tag |
| Tyr 466 | - | expression tag |
| Phe 467 | - | expression tag |
| Gln 468 | - | expression tag |
| Gly 469 | - | expression tag |
| Thr 470 | - | expression tag |
| Glu 471 | - | expression tag |
| Thr 472 | - | expression tag |
| Ser 473 | - | expression tag |
| Gln 474 | - | expression tag |
| Val 475 | - | expression tag |
| Ala 476 | - | expression tag |
| Pro 477 | - | expression tag |
| Ala 478 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 311749.1 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 4870.1 | |
| All* | Total formula weight | 316619.1 |
