8FQD
LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 10mM CaCl2, 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Ca10)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glutamate receptor 2 | polymer | 883 | 98854.9 | 4 | UniProt (P19491) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2 |
| 2 | E, G, I, K (A, B, C, D) | GLUTAMIC ACID | non-polymer | 147.1 | 4 | Chemie (GLU) | |||
| 3 | F, H, J, L (A, B, C, D) | CYCLOTHIAZIDE | non-polymer | 389.9 | 4 | Chemie (CYZ) | |||
| 4 | M, N (A, C) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 395419.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2148.0 | |
| All* | Total formula weight | 397567.4 |
