8FOW
Ternary complex of CDK2 with small molecule ligands TW8672 and Dinaciclib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cyclin-dependent kinase 2 | polymer | 298 | 33976.5 | 1 | UniProt (P24941) Pfam (PF00069) In PDB | Homo sapiens (human) | Cell division protein kinase 2,p33 protein kinase |
| 2 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 3 | A | 3-[({3-ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl}amino)methyl]-1-hydroxypyridinium | non-polymer | 397.5 | 1 | Chemie (1QK) | |||
| 4 | A | 2-{[2-(1H-indol-3-yl)ethyl]amino}-5-nitrobenzoic acid | non-polymer | 325.3 | 1 | Chemie (7TW) | |||
| 5 | water | water | 18.0 | 94 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33976.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 846.9 | |
| All* | Total formula weight | 34823.4 |
