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8FOJ

Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the post RNA handoff state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(1)
DNA polymerasepolymer1468167027.81UniProt (A0A8H4BVQ7)
Pfam (PF12254)
Pfam (PF03104)
Pfam (PF00136)
Pfam (PF08996)
UniProt (by SIFTS) (P13382)
Saccharomyces cerevisiae (baker's yeast)
2B
(A)
DNA primasepolymer40947760.41UniProt (A0A8H4C1R0)
Pfam (PF01896)
UniProt (by SIFTS) (P10363)
Saccharomyces cerevisiae (baker's yeast)
3C
(B)
DNA primase large subunitpolymer52862348.61UniProt (A0A6A5PVV0)
Pfam (PF04104)
UniProt (by SIFTS) (P20457)
Saccharomyces cerevisiae (baker's yeast)
4D
(C)
DNA polymerase alpha subunit Bpolymer70578865.91UniProt (A0A8H4F983)
Pfam (PF22062)
Pfam (PF04042)
UniProt (by SIFTS) (P38121)
Saccharomyces cerevisiae (baker's yeast)
5E
(T)
template DNApolymer113286.11synthetic construct
6F
(P)
Primer RNApolymer103279.11synthetic construct
7G
(B)
IRON/SULFUR CLUSTERnon-polymer351.61Chemie (SF4)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight362567.8
Non-Polymers*Number of molecules1
Total formula weight351.6
All*Total formula weight362919.5
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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