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8FOI

Native GABA-A receptor from the mouse brain, alpha1-beta2-gamma2 subtype, in complex with GABA and allopregnanolone

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, CGamma-aminobutyric acid receptor subunit alpha-1polymer45551818.52UniProt (P62812)
Pfam (PF02931)
Pfam (PF02932)
In PDB
Mus musculus (house mouse)GABA(A) receptor subunit alpha-1
2B, EGamma-aminobutyric acid receptor subunit beta-2polymer51259265.32UniProt (P63137)
Pfam (PF02931)
Pfam (PF02932)
In PDB
Mus musculus (house mouse)GABA(A) receptor subunit beta-2
3DGamma-aminobutyric acid receptor subunit gamma-2polymer47455160.31UniProt (P22723)
Pfam (PF02931)
Pfam (PF02932)
In PDB
Mus musculus (house mouse)GABA(A) receptor subunit gamma-2
4H, JHeavy Chain of 8E3 Fabpolymer22324159.92Mus musculus
5K, LLight Chain of 8E3-Fabpolymer21323624.12Mus musculus
6Falpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched1235.11In PDB
GlyTouCan (G07617FP)
7G, I, M, O, Palpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched910.85In PDB
GlyTouCan (G22768VO)
8Nbeta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched586.51In PDB
GlyTouCan (G15407YE)
9C, A[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoatenon-polymer746.62Chemie (PIO)
10E, B, C, A, DDODECANEnon-polymer170.317Chemie (D12)
11E, C, D, AN-OCTANEnon-polymer114.217Chemie (OCT)
12E, C, A(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphatenon-polymer760.15Chemie (POV)
13B, EGAMMA-AMINO-BUTANOIC ACIDnon-polymer103.12Chemie (ABU)
14B, Eallopregnanolonenon-polymer318.52Chemie (Y4B)
15D2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.21Chemie (NAG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains9
Total formula weight372895.9
BranchedNumber of molecules7
Total formula weight6375.8
Non-Polymers*Number of molecules46
Total formula weight11195.5
All*Total formula weight390467.2
*Water molecules are not included.

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PDB entries from 2024-08-28

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