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8FOG

Crystal structure of human DNA polymerase eta incorporating dITP across dT

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase etapolymer43248325.41UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
Homo sapiens (human)RAD30 homolog A,Xeroderma pigmentosum variant type protein
2B
(T)
DNA templatepolymer123557.31Homo sapiens
3C
(P)
DNA primerpolymer82506.71Homo sapiens
4D
(A)
2'-deoxyinosine 5'-triphosphatenon-polymer492.21Chemie (Y43)
5E
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
6F, G, H
(A, T, P)
waterwater18.043Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54389.4
Non-Polymers*Number of molecules2
Total formula weight532.2
All*Total formula weight54921.6
*Water molecules are not included.

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PDB entries from 2025-07-09

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