8FOB
Cryo-EM structure of human TRPV6 in the open state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Transient receptor potential cation channel subfamily V member 6 | polymer | 725 | 83302.8 | 4 | UniProt (Q9H1D0) Pfam (PF12796) Pfam (PF00023) Pfam (PF00520) | Homo sapiens (human) | TrpV6,CaT-like,CaT-L,Calcium transport protein 1,CaT1,Epithelial calcium channel 2,ECaC2 |
| 2 | CA, E, EA, F, FA... (C, A, B, D) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 12 | Chemie (Y01) | |||
| 3 | G, HA, TA, V (A, C, D, B) | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 787.1 | 4 | Chemie (PCW) | |||
| 4 | AA, BA, DA, H, I... (B, C, A, D) | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 28 | Chemie (POV) | |||
| 5 | P, Q (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | AB, BB, YA, ZA (C, D, A, B) | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 333211.3 | |
| Non-Polymers* | Number of molecules | 46 |
| Total formula weight | 30351.5 | |
| All* | Total formula weight | 363562.8 |
