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8FO6

Nucleotide-free structure of a functional construct of eukaryotic elongation factor 2 kinase.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Eukaryotic elongation factor 2 kinasepolymer53160380.71UniProt (O00418)
Pfam (PF02816)
Homo sapiens (human)eEF-2 kinase,eEF-2K,Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase
2B
(B)
Calmodulin-1polymer14816721.31UniProt (P0DP23)
Pfam (PF13499)
Homo sapiens (human)
3C
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
4D, E
(B)
CALCIUM IONnon-polymer40.12Chemie (CA)
5F, G
(A, B)
waterwater18.0107Chemie (HOH)
Sequence modifications
A: 70 - 483 (UniProt: O00418)
A: 490 - 725 (UniProt: O00418)
PDBExternal DatabaseDetails
Gly 484-linker
Gly 485-linker
Gly 486-linker
Gly 487-linker
Gly 488-linker
Gly 489-linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight77102.1
Non-Polymers*Number of molecules3
Total formula weight145.6
All*Total formula weight77247.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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