8FNY
Nucleotide-bound structure of a functional construct of eukaryotic elongation factor 2 kinase.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Eukaryotic elongation factor 2 kinase | polymer | 531 | 60380.7 | 2 | UniProt (O00418) Pfam (PF02816) | Homo sapiens (human) | eEF-2 kinase,eEF-2K,Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase |
| 2 | B, D (B, D) | Calmodulin-1 | polymer | 148 | 16721.3 | 2 | UniProt (P0DP23) Pfam (PF13499) | Homo sapiens (human) | |
| 3 | E, J (A, C) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 4 | F, K (A, C) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 5 | G, L (A, C) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | H, I, M, N (B, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 7 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 309 | Chemie (HOH) |
Sequence modifications
A, C: 70 - 483 (UniProt: O00418)
A, C: 490 - 725 (UniProt: O00418)
A, C: 490 - 725 (UniProt: O00418)
| PDB | External Database | Details |
|---|---|---|
| Gly 484 | - | linker |
| Gly 485 | - | linker |
| Gly 486 | - | linker |
| Gly 487 | - | linker |
| Gly 488 | - | linker |
| Gly 489 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 154204.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2159.9 | |
| All* | Total formula weight | 156364.0 |
