8FNB
Crystal structure of the C-terminal Fg domain of human TNC with the mutations Y2140H and S2164H
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tenascin | polymer | 231 | 26413.4 | 2 | UniProt (P24821) Pfam (PF00147) | Homo sapiens (human) | TN,Cytotactin,GMEM,GP 150-225,Glioma-associated-extracellular matrix antigen,Hexabrachion,JI,Myotendinous antigen,Neuronectin,Tenascin-C,TN-C |
| 2 | C, E (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 3 | D, F (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 433 | Chemie (HOH) |
Sequence modifications
A, B: 1975 - 2201 (UniProt: P24821)
| PDB | External Database | Details |
|---|---|---|
| Gly 1971 | - | expression tag |
| Thr 1972 | - | expression tag |
| Gly 1973 | - | expression tag |
| Ser 1974 | - | expression tag |
| His 2140 | Tyr 2140 | engineered mutation |
| His 2164 | Ser 2164 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52826.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 272.3 | |
| All* | Total formula weight | 53099.0 |
