8FN6

Cryo-EM structure of RNase-untreated RESC-A in trypanosomal RNA editing

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (g)	gRNA	polymer	46	14499.5	1		Trypanosoma brucei
2	B (1)	RNA-editing substrate-binding complex protein 1 (RESC1)	polymer	473	52608.7	1	UniProt (Q57XL7)	Trypanosoma brucei
3	C (2)	RNA-editing substrate-binding complex protein 2 (RESC2)	polymer	492	55526.1	1	UniProt (B6SBL9)	Trypanosoma brucei
4	D (3)	RNA-editing substrate-binding complex protein 3 (RESC3)	polymer	482	53146.6	1	UniProt (Q381A0)	Trypanosoma brucei
5	E (4)	RNA-editing substrate-binding complex protein 4 (RESC4)	polymer	1087	120847.9	1	UniProt (Q384R6)	Trypanosoma brucei
6	F (5)	RNA-editing substrate-binding complex protein 5 (RESC5)	polymer	402	43469.5	1	UniProt (Q389F5)	Trypanosoma brucei
7	G (6)	RNA-editing substrate-binding complex protein 6 (RESC6)	polymer	516	57823.5	1	UniProt (Q57ZX7)	Trypanosoma brucei
8	H (g)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	1	Chemie (ATP)

Sequence modifications

5: 1 - 310 (UniProt: Q389F5)

PDB	External Database	Details
Gly 311	-	expression tag
Ser 312	-	expression tag
Gly 313	-	expression tag
Ser 314	-	expression tag
Gly 315	-	expression tag
Ser 316	-	expression tag
Ala 317	-	expression tag
Ser 318	-	expression tag
Ser 319	-	expression tag
Gly 320	-	expression tag
Ala 321	-	expression tag
Ser 322	-	expression tag
Ala 323	-	expression tag
Ala 324	-	expression tag
Gly 325	-	expression tag
Ser 326	-	expression tag
Ser 327	-	expression tag
Gly 328	-	expression tag
Ala 329	-	expression tag
Ser 330	-	expression tag
Ala 331	-	expression tag
Ser 332	-	expression tag
Ser 333	-	expression tag
Gly 334	-	expression tag
Ala 335	-	expression tag
Ser 336	-	expression tag
Ala 337	-	expression tag
Ala 338	-	expression tag
Gly 339	-	expression tag
Ser 340	-	expression tag
Ser 341	-	expression tag
Gly 342	-	expression tag
Ala 343	-	expression tag
Ser 344	-	expression tag
Ala 345	-	expression tag
Gly 346	-	expression tag
His 347	-	expression tag
His 348	-	expression tag
His 349	-	expression tag
His 350	-	expression tag
His 351	-	expression tag
His 352	-	expression tag
His 353	-	expression tag
His 354	-	expression tag
His 355	-	expression tag
His 356	-	expression tag
Ser 357	-	expression tag
Gly 358	-	expression tag
Ser 359	-	expression tag
Glu 360	-	expression tag
Asp 361	-	expression tag
Gln 362	-	expression tag
Val 363	-	expression tag
Asp 364	-	expression tag
Pro 365	-	expression tag
Arg 366	-	expression tag
Leu 367	-	expression tag
Ile 368	-	expression tag
Asp 369	-	expression tag
Gly 370	-	expression tag
Lys 371	-	expression tag
Ala 372	-	expression tag
Ser 373	-	expression tag
Ala 374	-	expression tag
Trp 375	-	expression tag
Ser 376	-	expression tag
His 377	-	expression tag
Pro 378	-	expression tag
Gln 379	-	expression tag
Phe 380	-	expression tag
Glu 381	-	expression tag
Lys 382	-	expression tag
Gly 383	-	expression tag
Gly 384	-	expression tag
Gly 385	-	expression tag
Ser 386	-	expression tag
Gly 387	-	expression tag
Gly 388	-	expression tag
Gly 389	-	expression tag
Ser 390	-	expression tag
Gly 391	-	expression tag
Gly 392	-	expression tag
Ser 393	-	expression tag
Ala 394	-	expression tag
Trp 395	-	expression tag
Ser 396	-	expression tag
His 397	-	expression tag
Pro 398	-	expression tag
Gln 399	-	expression tag
Phe 400	-	expression tag
Glu 401	-	expression tag
Lys 402	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	397921.8
Non-Polymers*	Number of molecules	1
	Total formula weight	507.2
All*	Total formula weight	398428.9

*Water molecules are not included.