8FMM

Complex structure of wild type Troponin complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	Troponin C, slow skeletal and cardiac muscles	polymer	164	18673.6	2	UniProt (P63316) Pfam (PF13833) Pfam (PF13499) In PDB	Homo sapiens (human)	TN-C
2	B, E	Troponin T, cardiac muscle	polymer	109	13101.0	2	UniProt (P45379) Pfam (PF00992) In PDB	Homo sapiens (human)	TnTc,Cardiac muscle troponin T,cTnT
3	C, F	Troponin I, cardiac muscle	polymer	135	15405.9	2	UniProt (P19429) Pfam (PF00992) In PDB	Homo sapiens (human)	Cardiac troponin I
4	A, D	CALCIUM ION	non-polymer		40.1	6	Chemie (CA)

Sequence modifications

A, D: 1 - 161 (UniProt: P63316)

PDB	External Database	Details
Gln -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Ser 35	Cys 35	conflict
Ser 84	Cys 84	conflict
Glu 115	Asp 115	conflict

B, E: 183 - 288 (UniProt: P45379)

PDB	External Database	Details
Gln 180	-	expression tag
Gly 181	-	expression tag
Ser 182	-	expression tag

C, F: 32 - 166 (UniProt: P19429)

PDB	External Database	Details
Ala 80	Cys 80	conflict
Ala 97	Cys 97	conflict

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	94361.0
Non-Polymers*	Number of molecules	6
	Total formula weight	240.5
All*	Total formula weight	94601.5

*Water molecules are not included.