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8FLC

Human nuclear pre-60S ribosomal subunit (State K3)

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(BA)
60S ribosomal protein L12polymer16517847.61UniProt (P30050)
Pfam (PF03946)
Pfam (PF00298)
Homo sapiens (human)Large ribosomal subunit protein uL11
2B
(L1)
5.8S rRNApolymer15750463.81GenBank (555853)Homo sapiens (human)
3C
(L3)
28S rRNApolymer50701641203.81GenBank (86475748)Homo sapiens (human)
4D
(L4)
5S rRNApolymer12138998.11GenBank (23898)Homo sapiens (human)
5E
(L5)
60S ribosomal protein L11polymer17820288.51UniProt (P62913)
Pfam (PF00281)
Pfam (PF00673)
Homo sapiens (human)CLL-associated antigen KW-12,Large ribosomal subunit protein uL5
6F
(L6)
60S ribosomal protein L13polymer21124321.71UniProt (P26373)
Pfam (PF01294)
Homo sapiens (human)Breast basic conserved protein 1,Large ribosomal subunit protein eL13
7G
(L7)
60S ribosomal protein L13apolymer20323633.41UniProt (P40429)
Pfam (PF00572)
Homo sapiens (human)23 kDa highly basic protein,Large ribosomal subunit protein uL13
8H
(L8)
60S ribosomal protein L14polymer21523485.01UniProt (P50914)
Pfam (PF01929)
Homo sapiens (human)CAG-ISL 7,Large ribosomal subunit protein eL14
9I
(L9)
60S ribosomal protein L15polymer20424207.31UniProt (P61313)
Pfam (PF00827)
Homo sapiens (human)Large ribosomal subunit protein eL15
10J
(LA)
60S ribosomal protein L17polymer18421443.21UniProt (P18621)
Pfam (PF00237)
Homo sapiens (human)60S ribosomal protein L23,Large ribosomal subunit protein uL22,PD-1
11K
(LB)
60S ribosomal protein L18polymer18821687.71UniProt (Q07020)
Pfam (PF17135)
Homo sapiens (human)Large ribosomal subunit protein eL18
12L
(LC)
60S ribosomal protein L18apolymer17620808.51UniProt (Q02543)
Pfam (PF01775)
Homo sapiens (human)Large ribosomal subunit protein eL20
13M
(LD)
60S ribosomal protein L19polymer19623535.31UniProt (P84098)
Pfam (PF01280)
Homo sapiens (human)Large ribosomal subunit protein eL19
14N
(LE)
60S ribosomal protein L21polymer16018610.01UniProt (P46778)
Pfam (PF01157)
Homo sapiens (human)Large ribosomal subunit protein eL21
15O
(LF)
60S ribosomal protein L22polymer12814813.01UniProt (P35268)
Pfam (PF01776)
Homo sapiens (human)EBER-associated protein,EAP,Epstein-Barr virus small RNA-associated protein,Heparin-binding protein HBp15,Large ribosomal subunit protein eL22
16P
(LG)
60S ribosomal protein L23polymer14014892.51UniProt (P62829)
Pfam (PF00238)
Homo sapiens (human)60S ribosomal protein L17,Large ribosomal subunit protein uL14
17Q
(LH)
60S ribosomal protein L23apolymer15617740.21UniProt (P62750)
Pfam (PF03939)
Pfam (PF00276)
Homo sapiens (human)Large ribosomal subunit protein uL23
18R
(LI)
60S ribosomal protein L26polymer14517303.41UniProt (P61254)
Pfam (PF16906)
Pfam (PF00467)
Homo sapiens (human)Large ribosomal subunit protein uL24
19S
(LJ)
60S ribosomal protein L27polymer13615835.81UniProt (P61353)
Pfam (PF00467)
Pfam (PF01777)
Homo sapiens (human)Large ribosomal subunit protein eL27
20T
(LK)
60S ribosomal protein L27apolymer14816604.51UniProt (P46776)
Pfam (PF00828)
Homo sapiens (human)Large ribosomal subunit protein uL15
21U
(LL)
60S ribosomal protein L28polymer13715784.61UniProt (P46779)
Pfam (PF01778)
Homo sapiens (human)Large ribosomal subunit protein eL28
22V
(LM)
60S ribosomal protein L29polymer15917804.31UniProt (P47914)
Pfam (PF01779)
Homo sapiens (human)Cell surface heparin-binding protein HIP,Large ribosomal subunit protein eL29
23W
(LN)
60S ribosomal protein L3polymer40346224.11UniProt (P39023)
Pfam (PF00297)
Homo sapiens (human)HIV-1 TAR RNA-binding protein B,TARBP-B,Large ribosomal subunit protein uL3
24X
(LO)
60S ribosomal protein L30polymer11512805.11UniProt (P62888)
Pfam (PF01248)
Homo sapiens (human)Large ribosomal subunit protein eL30
25Y
(LP)
60S ribosomal protein L31polymer12514494.91UniProt (P62899)
Pfam (PF01198)
Homo sapiens (human)Large ribosomal subunit protein eL31
26Z
(LQ)
60S ribosomal protein L32polymer13515898.91UniProt (P62910)
Pfam (PF01655)
Homo sapiens (human)Large ribosomal subunit protein eL32
27AA
(LR)
60S ribosomal protein L34polymer11713326.11UniProt (P49207)
Pfam (PF01199)
Homo sapiens (human)Large ribosomal subunit protein eL34
28BA
(LS)
60S ribosomal protein L35polymer12314593.61UniProt (P42766)
Pfam (PF00831)
Homo sapiens (human)Large ribosomal subunit protein uL29
29CA
(LT)
60S ribosomal protein L35apolymer11012564.71UniProt (P18077)
Pfam (PF01247)
Homo sapiens (human)Cell growth-inhibiting gene 33 protein,Large ribosomal subunit protein eL33
30DA
(LU)
60S ribosomal protein L36polymer10512290.91UniProt (Q9Y3U8)
Pfam (PF01158)
Homo sapiens (human)Large ribosomal subunit protein eL36
31EA
(LV)
60S ribosomal protein L36apolymer10612477.01UniProt (J3KQN4)
Pfam (PF00935)
UniProt (by SIFTS) (P83881)
Homo sapiens (human)
32FA
(LW)
60S ribosomal protein L37polymer9711111.01UniProt (P61927)
Pfam (PF01907)
Homo sapiens (human)G1.16
33GA
(LX)
60S ribosomal protein L37apolymer9210299.41UniProt (P61513)
Pfam (PF01780)
Homo sapiens (human)Large ribosomal subunit protein eL43
34HA
(LY)
60S ribosomal protein L38polymer708238.91UniProt (P63173)
Pfam (PF01781)
Homo sapiens (human)
35IA
(LZ)
60S ribosomal protein L39polymer516426.81UniProt (P62891)
Pfam (PF00832)
Homo sapiens (human)
36JA
(NK)
Protein LLP homologpolymer12915268.41UniProt (Q9BRT6)
Pfam (PF10169)
Homo sapiens (human)Protein LAPS18-like
37KA
(NP)
Zinc finger protein 593polymer13415230.21UniProt (O00488)
Pfam (PF12171)
Homo sapiens (human)Zinc finger protein T86
38LA
(NR)
Translation machinery-associated protein 16polymer20323992.41UniProt (Q96EY4)
Pfam (PF11176)
Homo sapiens (human)
39MA
(SA)
60S ribosomal protein L4polymer42747804.61UniProt (P36578)
Pfam (PF00573)
Pfam (PF14374)
Homo sapiens (human)60S ribosomal protein L1,Large ribosomal subunit protein uL4
40NA
(SB)
60S ribosomal protein L5polymer29734426.81UniProt (P46777)
Pfam (PF17144)
Pfam (PF14204)
Homo sapiens (human)Large ribosomal subunit protein uL18
41OA
(SC)
60S ribosomal protein L6polymer28832810.21UniProt (Q02878)
Pfam (PF03868)
Pfam (PF01159)
Homo sapiens (human)Large ribosomal subunit protein eL6,Neoplasm-related protein C140,Tax-responsive enhancer element-binding protein 107,TaxREB107
42PA
(SD)
60S ribosomal protein L7polymer24829291.01UniProt (P18124)
Pfam (PF08079)
Pfam (PF00327)
Homo sapiens (human)Large ribosomal subunit protein uL30
43QA
(SE)
60S ribosomal protein L7apolymer26630061.81UniProt (P62424)
Pfam (PF01248)
Homo sapiens (human)Large ribosomal subunit protein eL8,PLA-X polypeptide,Surfeit locus protein 3
44RA
(SF)
60S ribosomal protein L8polymer25728088.91UniProt (P62917)
Pfam (PF00181)
Pfam (PF03947)
Homo sapiens (human)Large ribosomal subunit protein uL2
45SA
(SG)
60S ribosomal protein L9polymer19221899.51UniProt (P32969)
Pfam (PF00347)
Homo sapiens (human)Large ribosomal subunit protein uL6
46TA
(SK)
Eukaryotic translation initiation factor 6polymer24526620.01UniProt (P56537)
Pfam (PF01912)
Homo sapiens (human)eIF-6,B(2)GCN homolog,B4 integrin interactor,CAB,p27(BBP)
47UA
(SQ)
mRNA turnover protein 4 homologpolymer23927602.51UniProt (Q9UKD2)
Pfam (PF00466)
Pfam (PF17777)
Homo sapiens (human)Ribosome assembly factor MRTO4
48VA
(SR)
GTP-binding protein 4polymer63474107.81UniProt (Q9BZE4)
Pfam (PF17835)
Pfam (PF06858)
Pfam (PF08155)
Homo sapiens (human)Chronic renal failure gene protein,GTP-binding protein NGB,Nucleolar GTP-binding protein 1
49WA
(SV)
Probable ribosome biogenesis protein RLP24polymer16319666.31UniProt (Q9UHA3)
Pfam (PF01246)
Homo sapiens (human)Ribosomal L24 domain-containing protein 1,Ribosomal protein L24-like
50XA
(VB)
Leydig cell tumor 10 kDa protein homologpolymer9910605.71UniProt (Q9UNZ5)
Pfam (PF09495)
Homo sapiens (human)
51AB, AC, AD, AE, BB...
(L1, L3, LG, LN, LQ...)
MAGNESIUM IONnon-polymer24.388Chemie (MG)
52EE, GE, HE, JE, KE...
(LR, LV, LW, LX, NP...)
ZINC IONnon-polymer65.46Chemie (ZN)
53ME
(SR)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
54NE
(SR)
POTASSIUM IONnon-polymer39.11Chemie (K)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains50
Total formula weight2729539.5
Non-Polymers*Number of molecules96
Total formula weight3013.6
All*Total formula weight2732553.1
*Water molecules are not included.

227344

PDB entries from 2024-11-13

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