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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8FKU

Human nucleolar pre-60S ribosomal subunit (State C2)

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1BA60S ribosomal protein L12polymer16517847.61UniProt (P30050)
Pfam (PF03946)
Pfam (PF00298)
In PDB		Homo sapiens (human)Large ribosomal subunit protein uL11
2BB60S ribosomal protein L10apolymer21724879.41UniProt (P62906)
Pfam (PF00687)
In PDB		Homo sapiens (human)CSA-19,Large ribosomal subunit protein uL1,Neural precursor cell expressed developmentally down-regulated protein 6,NEDD-6
3L15.8S rRNApolymer15750449.81GenBank (555853)Homo sapiens (human)
4L2ITS2 rRNApolymer1167376425.31GenBank (86475748)Homo sapiens (human)
5L328S rRNApolymer50701640222.11GenBank (86475748)Homo sapiens (human)
6L660S ribosomal protein L13polymer21124321.71UniProt (P26373)
Pfam (PF01294)
In PDB		Homo sapiens (human)Breast basic conserved protein 1,Large ribosomal subunit protein eL13
7L760S ribosomal protein L13apolymer20323633.41UniProt (P40429)
Pfam (PF00572)
In PDB		Homo sapiens (human)23 kDa highly basic protein,Large ribosomal subunit protein uL13
8L860S ribosomal protein L14polymer21523485.01UniProt (P50914)
Pfam (PF01929)
In PDB		Homo sapiens (human)CAG-ISL 7,Large ribosomal subunit protein eL14
9L960S ribosomal protein L15polymer20424207.31UniProt (P61313)
Pfam (PF00827)
In PDB		Homo sapiens (human)Large ribosomal subunit protein eL15
10LA60S ribosomal protein L17polymer18421443.21UniProt (P18621)
Pfam (PF00237)
In PDB		Homo sapiens (human)60S ribosomal protein L23,Large ribosomal subunit protein uL22,PD-1
11LB60S ribosomal protein L18polymer18821687.71UniProt (Q07020)
Pfam (PF17135)
In PDB		Homo sapiens (human)Large ribosomal subunit protein eL18
12LC60S ribosomal protein L18apolymer17620808.51UniProt (Q02543)
Pfam (PF01775)
In PDB		Homo sapiens (human)Large ribosomal subunit protein eL20
13LE60S ribosomal protein L21polymer16018610.01UniProt (P46778)
Pfam (PF01157)
In PDB		Homo sapiens (human)Large ribosomal subunit protein eL21
14LG60S ribosomal protein L23polymer14014892.51UniProt (P62829)
Pfam (PF00238)
In PDB		Homo sapiens (human)60S ribosomal protein L17,Large ribosomal subunit protein uL14
15LH60S ribosomal protein L23apolymer15617740.21UniProt (P62750)
Pfam (PF03939)
Pfam (PF00276)
In PDB		Homo sapiens (human)Large ribosomal subunit protein uL23
16LI60S ribosomal protein L26polymer14517303.41UniProt (P61254)
Pfam (PF16906)
Pfam (PF00467)
In PDB		Homo sapiens (human)Large ribosomal subunit protein uL24
17LK60S ribosomal protein L27apolymer14816604.51UniProt (P46776)
Pfam (PF00828)
In PDB		Homo sapiens (human)Large ribosomal subunit protein uL15
18LL60S ribosomal protein L28polymer13715784.61UniProt (P46779)
Pfam (PF01778)
In PDB		Homo sapiens (human)Large ribosomal subunit protein eL28
19LN60S ribosomal protein L3polymer40346224.11UniProt (P39023)
Pfam (PF00297)
In PDB		Homo sapiens (human)HIV-1 TAR RNA-binding protein B,TARBP-B,Large ribosomal subunit protein uL3
20LQ60S ribosomal protein L32polymer13515898.91UniProt (P62910)
Pfam (PF01655)
In PDB		Homo sapiens (human)Large ribosomal subunit protein eL32
21LS60S ribosomal protein L35polymer12314593.61UniProt (P42766)
Pfam (PF00831)
In PDB		Homo sapiens (human)Large ribosomal subunit protein uL29
22LT60S ribosomal protein L35apolymer11012564.71UniProt (P18077)
Pfam (PF01247)
In PDB		Homo sapiens (human)Cell growth-inhibiting gene 33 protein,Large ribosomal subunit protein eL33
23LU60S ribosomal protein L36polymer10512290.91UniProt (Q9Y3U8)
Pfam (PF01158)
In PDB		Homo sapiens (human)Large ribosomal subunit protein eL36
24LW60S ribosomal protein L37polymer9711111.01UniProt (P61927)
Pfam (PF01907)
In PDB		Homo sapiens (human)G1.16
25NBGuanine nucleotide-binding protein-like 3polymer54962098.21UniProt (Q9BVP2)
Pfam (PF08701)
Pfam (PF01926)
In PDB		Homo sapiens (human)E2-induced gene 3 protein,Novel nucleolar protein 47,NNP47,Nucleolar GTP-binding protein 3,Nucleostemin
26NFRibosome biogenesis protein NSA2 homologpolymer26030136.71UniProt (O95478)
Pfam (PF01201)
In PDB		Homo sapiens (human)Hairy cell leukemia protein 1,TGF-beta-inducible nuclear protein 1
27NH60S ribosome subunit biogenesis protein NIP7 homologpolymer18020491.61UniProt (Q9Y221)
Pfam (PF17833)
Pfam (PF03657)
In PDB		Homo sapiens (human)KD93,Nucleolar pre-rRNA processing protein NIP7
28NIATP-dependent RNA helicase DDX54polymer88198769.21UniProt (Q8TDD1)
Pfam (PF00270)
Pfam (PF00271)
Pfam (PF08147)
In PDB		Homo sapiens (human)ATP-dependent RNA helicase DP97,DEAD box RNA helicase 97 kDa,DEAD box protein 54
29NKProtein LLP homologpolymer12915268.41UniProt (Q9BRT6)
Pfam (PF10169)
In PDB		Homo sapiens (human)Protein LAPS18-like
30SA60S ribosomal protein L4polymer42747804.61UniProt (P36578)
Pfam (PF00573)
Pfam (PF14374)
In PDB		Homo sapiens (human)60S ribosomal protein L1,Large ribosomal subunit protein uL4
31SC60S ribosomal protein L6polymer28832810.21UniProt (Q02878)
Pfam (PF03868)
Pfam (PF01159)
In PDB		Homo sapiens (human)Large ribosomal subunit protein eL6,Neoplasm-related protein C140,Tax-responsive enhancer element-binding protein 107,TaxREB107
32SD60S ribosomal protein L7polymer24829291.01UniProt (P18124)
Pfam (PF08079)
Pfam (PF00327)
In PDB		Homo sapiens (human)Large ribosomal subunit protein uL30
33SE60S ribosomal protein L7apolymer26630061.81UniProt (P62424)
Pfam (PF01248)
In PDB		Homo sapiens (human)Large ribosomal subunit protein eL8,PLA-X polypeptide,Surfeit locus protein 3
34SG60S ribosomal protein L9polymer19221899.51UniProt (P32969)
Pfam (PF00347)
In PDB		Homo sapiens (human)Large ribosomal subunit protein uL6
35SHMKI67 FHA domain-interacting nucleolar phosphoproteinpolymer29334285.31UniProt (Q9BYG3)
Pfam (PF00076)
Pfam (PF12196)
In PDB		Homo sapiens (human)Nucleolar phosphoprotein Nopp34,Nucleolar protein interacting with the FHA domain of pKI-67,hNIFK
36SI60S ribosomal protein L7-like 1polymer25529730.41UniProt (Q6DKI1)
Pfam (PF08079)
Pfam (PF00327)
In PDB		Homo sapiens (human)Large ribosomal subunit protein uL30-like 1
37SJpre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3polymer84796726.91UniProt (Q8IY81)
Pfam (PF01728)
Pfam (PF11861)
Pfam (PF07780)
In PDB		Homo sapiens (human)Protein ftsJ homolog 3,Putative rRNA methyltransferase 3
38SKEukaryotic translation initiation factor 6polymer24526620.01UniProt (P56537)
Pfam (PF01912)
In PDB		Homo sapiens (human)eIF-6,B(2)GCN homolog,B4 integrin interactor,CAB,p27(BBP)
39SLRibosomal L1 domain-containing protein 1polymer49055089.81UniProt (O76021)
Pfam (PF00687)
In PDB		Homo sapiens (human)CATX-11,Cellular senescence-inhibited gene protein,Protein PBK1
40SMPescadillo homologpolymer58868114.71UniProt (O00541)
Pfam (PF06732)
Pfam (PF16589)
In PDB		Homo sapiens (human)
41SNProbable rRNA-processing protein EBP2polymer30634925.11UniProt (Q99848)
Pfam (PF05890)
In PDB		Homo sapiens (human)EBNA1-binding protein 2,Nucleolar protein p40
42SORibosome biogenesis protein BRX1 homologpolymer35341483.51UniProt (Q8TDN6)
Pfam (PF04427)
In PDB		Homo sapiens (human)Brix domain-containing protein 2
43SQmRNA turnover protein 4 homologpolymer23927602.51UniProt (Q9UKD2)
Pfam (PF00466)
Pfam (PF17777)
In PDB		Homo sapiens (human)Ribosome assembly factor MRTO4
44SRGTP-binding protein 4polymer63474107.81UniProt (Q9BZE4)
Pfam (PF17835)
Pfam (PF06858)
Pfam (PF08155)
In PDB		Homo sapiens (human)Chronic renal failure gene protein,GTP-binding protein NGB,Nucleolar GTP-binding protein 1
45SSRibosome biogenesis protein BOP1polymer74683901.51UniProt (Q14137)
Pfam (PF08145)
Pfam (PF00400)
In PDB		Homo sapiens (human)Block of proliferation 1 protein
46STRibosome biogenesis regulatory protein homologpolymer36541278.51UniProt (Q15050)
Pfam (PF04939)
In PDB		Homo sapiens (human)
47SVProbable ribosome biogenesis protein RLP24polymer16319666.31UniProt (Q9UHA3)
Pfam (PF01246)
In PDB		Homo sapiens (human)Ribosomal L24 domain-containing protein 1,Ribosomal protein L24-like
48SWATP-dependent RNA helicase DDX18polymer67075526.81UniProt (Q9NVP1)
Pfam (PF00270)
Pfam (PF00271)
Pfam (PF13959)
In PDB		Homo sapiens (human)DEAD box protein 18,Myc-regulated DEAD box protein,MrDb
49SYProbable 28S rRNA (cytosine(4447)-C(5))-methyltransferasepolymer81289441.81UniProt (P46087)
Pfam (PF17125)
Pfam (PF01189)
Pfam (PF08062)
In PDB		Homo sapiens (human)Nucleolar protein 1,Nucleolar protein 2 homolog,Proliferating-cell nucleolar antigen p120,Proliferation-associated nucleolar protein p120
50SZNucleolar protein 16polymer17821234.51UniProt (Q9Y3C1)
Pfam (PF09420)
In PDB		Homo sapiens (human)HBV pre-S2 trans-regulated protein 3
51L1, L3, L2, NI, SA...MAGNESIUM IONnon-polymer24.358Chemie (MG)
52LW, SVZINC IONnon-polymer65.42Chemie (ZN)
53NIADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
54SRGUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
55SRPOTASSIUM IONnon-polymer39.11Chemie (K)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains50
Total formula weight3691396.1
Non-Polymers*Number of molecules63
Total formula weight2450.0
All*Total formula weight3693846.1
*Water molecules are not included.

219515

PDB entries from 2024-05-08

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