8FJW
Human GAR transformylase in complex with GAR substrate and AGF347 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Trifunctional purine biosynthetic protein adenosine-3 | polymer | 210 | 22810.1 | 1 | UniProt (P22102) Pfam (PF00551) | Homo sapiens (human) | |
| 2 | B (A) | GLYCINAMIDE RIBONUCLEOTIDE | non-polymer | 284.2 | 1 | Chemie (GAR) | |||
| 3 | C (A) | N-{4-[4-(2-amino-4-oxo-3,4-dihydro-5H-pyrrolo[3,2-d]pyrimidin-5-yl)butyl]-2-fluorobenzoyl}-L-glutamic acid | non-polymer | 473.5 | 1 | Chemie (Y79) | |||
| 4 | D (A) | water | water | 18.0 | 91 | Chemie (HOH) |
Sequence modifications
A: 808 - 1010 (UniProt: P22102)
| PDB | External Database | Details |
|---|---|---|
| Met 807 | - | initiating methionine |
| His 1011 | - | expression tag |
| His 1012 | - | expression tag |
| His 1013 | - | expression tag |
| His 1014 | - | expression tag |
| His 1015 | - | expression tag |
| His 1016 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 22810.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 757.6 | |
| All* | Total formula weight | 23567.8 |
