8FIL
Zinc-free APOBEC3A (inactive E72A mutant) in complex with TTC-hairpin DNA substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA dC->dU-editing enzyme APOBEC-3A | polymer | 199 | 22983.0 | 2 | UniProt (P31941) Pfam (PF05240) | Homo sapiens (human) | A3A,Phorbolin-1 |
| 2 | C, D (D, E) | DNA (5'-D(*TP*GP*CP*GP*CP*TP*TP*CP*GP*CP*GP*CP*T)-3') | polymer | 13 | 3934.5 | 2 | Homo sapiens | ||
| 3 | E, G (A, B) | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 2 | Chemie (IHP) | |||
| 4 | F, H (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | I, J, K, L (A, B, D, E) | water | water | 18.0 | 81 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 199 (UniProt: P31941)
| PDB | External Database | Details |
|---|---|---|
| Ala 72 | Glu 72 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 53835.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1391.0 | |
| All* | Total formula weight | 55226.0 |
