8FI9

Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody WRAIR-5001

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, K, O	Spike protein S1	polymer	205	23073.8	4	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 2019-nCoV COVID-19 virus)
2	F, I, L, N	WRAIR-5001 Fab Light chain	polymer	215	22972.3	4		Macaca mulatta
3	G, H, J, Q	WRAIR-5001 Fab Heavy chain	polymer	223	24118.0	4		Macaca mulatta
4	A, C, K, O	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
5	H, J, N, O, Q	GLYCEROL	non-polymer		92.1	10	Chemie (GOL)
6		water	water		18.0	4	Chemie (HOH)

Sequence modifications

A, C, K, O: 331 - 527 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 528	-	expression tag
Ser 529	-	expression tag
His 530	-	expression tag
His 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	280656.2
Non-Polymers*	Number of molecules	14
	Total formula weight	1805.8
All*	Total formula weight	282462.0

*Water molecules are not included.