8FI9
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody WRAIR-5001
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, H, K (A, C, K, O) | Spike protein S1 | polymer | 205 | 23073.8 | 4 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 2019-nCoV COVID-19 virus) | |
| 2 | C, F, I, J (F, I, L, N) | WRAIR-5001 Fab Light chain | polymer | 215 | 22972.3 | 4 | Macaca mulatta | ||
| 3 | D, E, G, L (G, H, J, Q) | WRAIR-5001 Fab Heavy chain | polymer | 223 | 24118.0 | 4 | Macaca mulatta | ||
| 4 | M, N, R, V (A, C, K, O) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 5 | O, P, Q, S, T... (H, J, N, O, Q) | GLYCEROL | non-polymer | 92.1 | 10 | Chemie (GOL) | |||
| 6 | AA (H) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, C, K, O: 331 - 527 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 528 | - | expression tag |
| Ser 529 | - | expression tag |
| His 530 | - | expression tag |
| His 531 | - | expression tag |
| His 532 | - | expression tag |
| His 533 | - | expression tag |
| His 534 | - | expression tag |
| His 535 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 280656.2 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1805.8 | |
| All* | Total formula weight | 282462.0 |
